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Nov 1, 2004 · Glucocorticoids in the treatment of rheumatic diseases: an update on the mechanisms of action.
Jan 1, 2024 · During the period 2020–2023, the Annals of the Rheumatic Diseases published several original papers, brief reports and letters that further elucidate the mechanisms of action …
The various mechanisms of action provide inter-esting and sometimes very advanced starting points for the development of optimized GCs and GCR ligands. We will now take a brief look at …
Nov 4, 2004 · The various mechanisms of action provide interesting and sometimes very advanced starting points for the development of optimized GCs and GCR ligands. We will now take a brief …
MeSH terms Glucocorticoids / therapeutic use* Humans Rheumatic Diseases / drug therapy*
Dec 1, 2011 · In this review, we describe new insights into the mechanisms of anti-inflammatory glucocorticoid actions and provide an update on recent approaches to improve the risk/benefit …
Dec 1, 2004 · We confirm that glucocorticoid administration is associated with disease activity and lack of response. This is supported by the historical indication and mechanism of action of...
There is an ongoing quest for new drugs with glucocorticoid actions without the potential to cause harmful effects, such as selective glucocorticoid receptor agonists, but the application of a new …
Abstract Therapeutic glucocorticoids have been widely used in rheumatic diseases since they became available over 60 years ago. Despite the advent of more specific biologic therapies, a …
Feb 7, 2020 · Understanding the pharmacokinetic properties and mechanisms of action of glucocorticoids could inform in the development of novel therapies with fewer adverse effects.
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